A Legacy of Surgical Excellence
CardioNova Therapeutics has been a trusted partner to cardiac surgeons for over five decades. Our surgical heart valve portfolio features the most advanced tissue and mechanical valve technologies available, designed to deliver exceptional hemodynamic performance and long-term durability.
NovaResilience™ Bioprosthetic Valve Family
The NovaResilience™ family combines CardioNova's proprietary Resilia™ tissue technology with proven bovine pericardial design, delivering superior hemodynamics and demonstrated long-term structural integrity.
Resilia™ tissue is designed to reduce calcification and maintain valve durability beyond 10 years — a critical advantage for younger patients who are increasingly receiving surgical bioprostheses.
- ✓ Resilia™ anti-calcification tissue technology
- ✓ Low transvalvular gradients across all sizes
- ✓ Supra-annular design for maximized EOA
- ✓ Optimized for future valve-in-valve TAVR
- ✓ Available in 19–29mm annular sizes
NovaResilience™ Aortic Valve
Our flagship surgical aortic bioprosthesis with Resilia™ tissue and a proven supra-annular stented design for patients of all ages.
Product Details
NovaResilience™ Mitral Valve
Designed specifically for the mitral position with asymmetric sewing cuff and optimized leaflet geometry for superior central flow.
Product Details
NovaResilience™ Stentless Root
A full root stentless bioprosthesis offering the most physiologic flow profile — preferred for complex aortic root surgery including Bentall procedures.
Product DetailsMechanical Heart Valves
For patients requiring lifelong valve replacement with maximum durability, CardioNova's mechanical valves offer decades of proven performance.
NovaMech™ Bileaflet Mechanical Valve
The NovaMech™ series features our proprietary pyrolytic carbon leaflet design with superior fatigue resistance and thromboresistance. Available in aortic and mitral configurations.
- ✓ Pyrolytic carbon leaflets and housing
- ✓ Low-profile design for limited surgical access
- ✓ MRI conditional up to 3T
- ✓ Over 30 years of clinical follow-up data
Anticoagulation Management Support
Patients with mechanical valves require lifelong anticoagulation. CardioNova provides comprehensive resources to support anticoagulation management for surgical teams and patients.
Access Resources →Mitral & Tricuspid Repair Products
Valve repair is preferred over replacement whenever anatomy allows. CardioNova's comprehensive repair portfolio supports surgeons in achieving durable repair outcomes.
NovaRing™ Complete Annuloplasty System
A complete line of rigid, semi-rigid, and flexible annuloplasty rings for mitral and tricuspid repair, in both full and partial configurations.
Product Details →NovaPatch™ Pericardial Repair Patch
Bovine pericardium treated with Resilia™ technology for leaflet reconstruction, augmentation, and fenestration repair in mitral and aortic valve surgery.
Product Details →NovaChord™ ePTFE Chord System
Pre-measured ePTFE neochord loops that simplify chordal reconstruction in minimally invasive and robotic mitral valve repair procedures.
Product Details →Hemodynamic Monitoring
Accurate hemodynamic data during and after cardiac surgery helps guide surgical decision-making and optimize patient outcomes.
NovaPAP™ Pulmonary Artery Monitoring
A minimally invasive implantable pulmonary artery pressure sensor that enables remote hemodynamic monitoring in heart failure and post-surgical patients.
Learn More →NovaSense™ Intraoperative Flow Probe
An ultrasonic transit-time flow measurement system for real-time coronary and graft flow assessment during cardiac and vascular surgery.
Learn More →CardioStat™ Cardiac Output Monitor
Continuous minimally invasive cardiac output and stroke volume monitoring for the OR and ICU — providing actionable hemodynamic parameters without arterial catheterization.
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Clinical Evidence
RESILIENCE Trial — 10-Year Outcomes
Long-term data demonstrating significantly reduced structural valve deterioration with Resilia™ tissue compared to standard glutaraldehyde-preserved valves.
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NovaMech™ 30-Year Safety Review
A pooled analysis of 30 years of NovaMech™ mechanical valve follow-up across 18 centers demonstrating excellent structural integrity and thromboembolic outcomes.
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Surgical Repair Outcomes Registry
A prospective registry of mitral valve repair outcomes using NovaRing™ annuloplasty systems across 85 international centers.
View Registry →