Transforming Structural Heart Care
CardioNova Therapeutics is a global leader in transcatheter heart valve therapies, pioneering catheter-based techniques to treat valvular heart disease in patients who may not be candidates for conventional surgery.
Transcatheter Aortic Valve Replacement
TAVR (also known as TAVI) is a minimally invasive procedure that replaces a diseased aortic valve without removing the old valve. A new valve is compressed onto a delivery catheter and guided through the vasculature to the heart, where it expands and immediately takes over valve function.
CardioNova's TAVR platform — the NovaCor™ Transcatheter Aortic Heart Valve System — has been used in over 1 million procedures worldwide, with a demonstrated safety and effectiveness profile across all surgical risk categories.
- ✓ Available in multiple sizes to fit diverse patient anatomies
- ✓ Repositionable and retrievable delivery system
- ✓ Superior hemodynamic performance
- ✓ Compatible with the NovaSight™ implant detection technology
Our Transcatheter Valve Portfolio
NovaCor™ Elite Transcatheter Heart Valve
Our next-generation TAVR system with enhanced conformability, reduced paravalvular leak, and an ultra-low profile delivery catheter for challenging anatomies.
Product Details
NovaCor™ Pro Transcatheter Heart Valve
Designed for intermediate and high surgical risk patients, the NovaCor™ Pro offers exceptional valve-in-valve performance and established 5-year durability data.
Product Details
NovaFlow™ Transcatheter Mitral Valve System
A breakthrough transcatheter mitral valve replacement system for patients with severe mitral regurgitation who are at high or prohibitive surgical risk.
Product DetailsTranscatheter Mitral Valve Repair & Replacement
Mitral valve disease affects millions worldwide. CardioNova is advancing multiple transcatheter approaches to address the full spectrum of mitral pathology.
NovaClip™ Mitral Valve Repair
A catheter-based leaflet repair system for patients with symptomatic moderate-to-severe mitral regurgitation who remain at high risk for surgery despite optimal medical therapy.
Learn More →NovaFlow™ Mitral Replacement
Transcatheter mitral valve replacement for patients with failed surgical bioprostheses or complex native mitral disease not amenable to repair.
Learn More →NovaAnchor™ Annuloplasty Ring
A transcatheter annuloplasty system that restores the mitral annulus geometry to facilitate successful mitral valve repair.
Learn More →Tricuspid Valve Therapies
Tricuspid regurgitation is a serious and often under-treated condition. CardioNova's tricuspid portfolio offers multiple therapeutic options.
NovaTri™ Tricuspid Valve Repair System
A transcatheter coaptation device that addresses tricuspid regurgitation by improving leaflet coaptation — reducing regurgitation without open-heart surgery.
- ✓ Deployed via femoral venous access
- ✓ Adjustable post-implant
- ✓ CE Mark approved; FDA Breakthrough Device
NovaTri™ Replace Transcatheter Tricuspid Valve
A transcatheter tricuspid valve replacement system for patients with severe native tricuspid regurgitation, offering a bioprosthetic replacement option without surgery.
- ✓ Self-expanding nitinol frame
- ✓ Resilia™ treated pericardial tissue
- ✓ Currently in pivotal clinical trial
Clinical Evidence
Our transcatheter therapies are backed by the most comprehensive clinical trial programs in structural heart disease.
NOVA-TAVR Low Risk Trial
5-year outcomes demonstrating NovaCor™ Elite superiority over surgical aortic valve replacement in low surgical risk patients with severe aortic stenosis.
View Data →CardioNova Global Registry
Real-world data from over 250 centers across 40 countries tracking long-term outcomes with NovaCor™ transcatheter valves.
View Registry →NOVA-FLOW Mitral Registry
One-year outcomes of the NovaFlow™ transcatheter mitral valve replacement system in patients with failed surgical bioprostheses.
Read Publication →Training & Education
CardioNova is committed to training the next generation of structural heart specialists through world-class programs.
Proctor & Training Program
A structured pathway to independence for TAVR, TMVR, and tricuspid procedures — combining simulation, proctored cases, and expert mentorship.
Request Training →Online Learning Portal
On-demand modules, procedural videos, case studies, and product tutorials accessible anytime through the CardioNova Professional portal.
Access Portal →Simulation Labs
State-of-the-art simulation centers at major academic institutions equipped with CardioNova implant simulators and live animal model capabilities.
Find a Lab →