What is a clinical trial?
A clinical trial involving a medical device is a voluntary study conducted in people and designed to answer specific questions about the safety and effectiveness of the device for a specific use or a use that may not otherwise be available, usually comparing the intervention with a device against a control group.
Clinical trials are conducted in phases, each designed to answer different questions about the therapy being studied. CardioNova Therapeutics maintains one of the most comprehensive clinical trial programs in the structural heart disease space.
Participation in a clinical trial may give you access to new therapies before they are widely available and contributes to the advancement of medical knowledge that helps future patients.
Patient Engagement in Clinical Research
Patient engagement is central to the success of clinical research. CardioNova Therapeutics works closely with patients and advocacy groups to design studies that reflect what matters most to those living with heart valve disease.
Why Participate?
Clinical trial participants may gain access to cutting-edge treatments before they're commercially available, receive close monitoring from specialists, and contribute to scientific knowledge that benefits future patients.
Your Rights as a Participant
Participation is always voluntary. You have the right to withdraw at any time without affecting your standard medical care. All studies require informed consent reviewed and approved by an institutional review board (IRB).
What to Expect
Participants undergo regular assessments and follow-ups. The study team provides detailed information about procedures, potential risks and benefits, and any costs or compensation involved.
Find a Trial Near You
Use our trial finder to search for CardioNova Therapeutics-sponsored clinical trials currently enrolling patients at centers worldwide.
Trial Search
NOVA-TAVI III — Transcatheter Aortic Valve Replacement Study
Phase III • Aortic Stenosis • Enrolling Now • Multiple US & International Centers
View Trial Details →NOVA-CLIP Registry — Transcatheter Mitral Repair
Registry Study • Mitral Regurgitation • Enrolling Now • US, EU, Asia-Pacific
View Trial Details →TRISCEND II Pivotal Trial — Transcatheter Tricuspid Replacement
Phase III • Tricuspid Regurgitation • Enrolling Now • Select Centers Globally
View Trial Details →RESILIENCE Study — Long-Term Durability of RESILIA™ Tissue
Post-Market Surveillance • Aortic & Mitral • Follow-Up Study
View Trial Details →Long-Term Follow-Up
CardioNova Therapeutics is committed to understanding the long-term performance of our therapies. Our registries and long-term follow-up programs track patient outcomes for 5, 10, and even 20 years post-procedure.
This commitment to long-term evidence generation is fundamental to our mission of improving patient outcomes and advancing the science of structural heart therapy.
If you have previously participated in a CardioNova clinical study, your continued participation in follow-up is invaluable to the advancement of medical science.
Contact Our Study TeamPublished Studies & Outcomes
Our clinical evidence portfolio includes landmark trials published in leading peer-reviewed journals.
PARTNER 3 Trial — 5-Year Outcomes
New England Journal of Medicine →COAPT Trial — 3-Year Follow-Up
Journal of the American College of Cardiology →Resources
Patient Guide to Clinical Trials
A comprehensive guide explaining clinical trial phases, your rights, and what to expect as a participant.
Download PDF →Questions to Ask Your Doctor
A helpful list of questions to guide your conversation with your heart care team about clinical trial participation.
Download PDF →ClinicalTrials.gov
Search the U.S. National Library of Medicine's database of clinical studies worldwide.
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